Why We Ask ‘What If’?

VentureWell 30th Anniversary; photo of President and CEO Phil Weilerstein, tinted background collage with photos from company’s history

VentureWell President and CEO Phil Weilerstein Reflects on 30 Years

Roughly 15 years ago, I sat in a crowded room of innovators at Stanford University as we kicked off a first-of-its-kind program designed to translate scientific discoveries into real-world applications. A colleague leaned over and asked quietly, “Phil, what if this doesn’t work?”

It was an honest question; in fact, one that speaks to the very heart of innovation. In that Stanford classroom all those years ago, I found that uncertainty can bring its own kind of clarity. Success in this work has never required certainty. It requires willingness—to take risks, try, learn, and persevere.

That ethos of experimentation has powered VentureWell since the beginning.

For 30 years, we have been dedicated to catalyzing innovation in service of people and the planet. Our founding, guided by the vision of the prolific inventor Jerry Lemelson, was driven by the belief that invention could help solve the world’s greatest challenges and should be fostered through education and support.

Indeed, Jerry had a singular ability to anticipate what others could not yet see. He envisioned a future in which students from all backgrounds would work on problems that mattered, create meaningful solutions, and, in doing so, build companies, careers, and communities of impact.

In the early days, we faced skepticism. Were we leading students into unnecessary risks? Was entrepreneurship a legitimate career path? Would our model endure? Was it actually scalable?

But we stayed the course. We understood that bold ideas, especially those rooted in systems change, are rarely readily accepted—they must be championed with persistence, partnership, process, and adaptability.

When we assembled a community of faculty for the first national convening in 1997 to validate and launch our higher education programming, we gathered just over 100 people from a wide range of disciplines and backgrounds. In the nascent days of the internet, we found these early adopters one by one: people who believed in an entrepreneurial approach to engineering and science education—one that encouraged creativity, collaboration, and practical application. What we discovered in that meeting was profound and empowering; there was, in fact, a growing community ready to build this vision together.

That moment helped shape what VentureWell has become: a trusted partner in innovation, working to make the improbable possible and the possible scalable.

It is often surprising how much can be accomplished with relatively modest resources when those resources are applied with clear, thoughtful intention. Equally powerful is the impact of bringing together a community of like-minded people, united by shared goals and a willingness to learn from one another. That catalytic quality of enabling something larger than the sum of its parts has been core to our model from the outset.

Over the past 30 years, we’ve enabled the launch of more than 5,800 ventures, trained over 19,000 innovators, awarded upwards of $30 million in grants, partnered with more than a thousand higher education institutions, and supported innovators in 55+ countries, reaching millions of people worldwide.

Throughout this journey, I have been continually inspired by both the organizational outcomes and the individual transformations. Seeing an emerging innovator gain the confidence to pursue a game-changing invention or watching a faculty member shift an entire curriculum to foster innovation remains deeply meaningful. These moments affirm that we are building not just new ventures and transformative programs, but, taken together, an innovation pathway that leads us toward a more equitable and innovative society.

We now find ourselves at a new inflection point. Higher education is undergoing a significant transformation. Public investment structures are shifting. The U.S. is projected to face a shortage of 1.4 million STEM workers, including technicians, computer scientists, and engineers, by 2030. Our charge to make innovation pathways accessible is more urgent than ever. Meeting this moment will require not only new approaches but renewed commitment to our vision of building a world where all innovators can improve lives and protect the planet.

We are reaffirming that commitment today. As VentureWell enters its next chapter, our work will evolve to meet the challenges ahead. And we will continue to take a bold, all-in approach, cultivating emerging talent and surfacing untapped potential. Together, we will advance scientific innovation that is groundbreaking, purposeful, and accessible. Innovation in service of all.

It has been one of the great privileges of my life to lead this organization from its inception and to learn, adapt, and build in partnership with so many extraordinary individuals and partner organizations. I am deeply proud of what we have created together: a model that is impactful and principled.

To all who have been part of this journey, thank you for making this work possible—and profoundly meaningful. Here’s to what we’ve built and what we’ll build next.

And here’s to the next 30 years of asking, “What if this doesn’t work?”—and daring to try anyway.


Phil Weilerstein has led VentureWell since its founding in 1995 and today serves as president and CEO. By developing and expanding VentureWell’s programs on a national and global scale, Phil has helped advance VentureWell’s mission to solve global challenges through science- and technology-driven innovation and entrepreneurship. Phil is committed to sharing VentureWell’s learnings and resources to support the creation of inclusive and more equitable pathways for student innovators to succeed in venture creation. Under Phil’s leadership, VentureWell has collaborated with key science funding agencies, major philanthropies, and hundreds of universities to train and support thousands of emerging students, researchers, and faculty innovators.

Phil attended the University of Massachusetts, where he was a co-founder of a biotechnology company developing naturally occurring pest control products. He is a founder and past chair of the ASEE Entrepreneurship Division, and a recipient of the 2008 Price Foundation Innovative Entrepreneurship Educators Award, the 2014 Engineering Entrepreneurship Pioneers Award from ASEE, the 2016 Deshpande Symposium Award for Outstanding Contributions to Advancing Innovation and Entrepreneurship in Higher Education, and a 2025 Sentinel Award from the National Academy of Inventors.

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